revolutionizing The stem cell Transplant PATIENT experience

Magenta is advancing a unique and fully integrated pipeline of product candidates designed to bring the curative power of stem cell transplant to more patients with blood cancers, genetic diseases and autoimmune diseases.

Stem Cell Mobilization & Collection Program: Our MGTA-145 program is focused on enabling rapid, reliable, predictable and well-tolerated mobilization and collection of sufficient numbers of highly functional stem cells for transplant from both patients and donors.

Targeted Conditioning Program: Our MGTA-117 program is focused on selectively depleting stem cells from patients who are preparing for transplant or gene therapy to make space in the bone marrow for new transplanted stem cells or gene modified cells.  Targeted depletion is designed to reduce the need for high-dose or high-intensity chemotherapy or, in the case of gene therapy applications, to potentially eliminate the need for chemotherapy altogether.

Conditioning Research Platform: Our targeted conditioning research platform seeks to identify and advance the next generation of candidates that selectively deplete stem cells and/or immune cells from a patient prior to transplant, or HSC-based gene therapy. These programs focus on developing products that remove specific cell types, with an approach that is tailored to the patient’s disease and transplant requirements. Initial applications of our research-stage programs include broad conditioning to support both autologous and allogeneic bone marrow transplant, immune reset for autoimmune diseases, and ; lymphodepletion prior to cell therapies such as CAR-T.

Magenta Therapeutics Portfolio

Privacy Preference Center

Advertising

The NID and IDE cookies are set by DoubleClick (which is owned by Google) to help build a profile of your interests and show you relevant ads on other sites. The 1P_JAR cookie (from google.com) carries out information about how the end user uses the website and any advertising that the end user may have seen before visiting the said website.

NID, IDE, 1P_JAR

Analytics

Magenta TX uses these cookies to collect information about how visitors use our Site. We use the information to compile reports and to help us improve the Site. The cookies collect information in an anonymous form, including the number of visitors to the Site, where visitors have come to the Site from and the pages they visited. If you do not allow these cookies we will not be able to include your visit in our statistics. You can read the full Google Analytics privacy policy at: https://www.google.com/policies/privacy/.

_ga,_gat,_gid, _gali

Other

Functionality

The OGPC cookie enables the functionality of Google Maps. s_cc Adobe Site Catalyst cookie, determines whether cookies are enabled in the browser. The s_sq and s_vi, Adobe Site Catalyst cookie, stores information about the previous link clicked within the site as well as identify unique visitors, with an ID and timestamp.

OGPC, s_cc, s_sq, s_vi