Currently, only a fraction of patients receive a transplant because the risks and challenges outweigh the potential for a cure.
Immune reset through transplant is a 2-step process:
- Step 1: Removing the disease-causing cells
- Step 2: Replacing them with healthy cells to rebuild the immune system to a healthy state
All stem cell transplants are categorized as either autologous or allogeneic, depending on the source of the healthy cells for the transplant. In an autologous transplant, used for conditions such as autoimmune diseases and multiple myeloma, the patient’s own stem cells are used. This is also the case for stem cell gene therapy for genetic diseases such as sickle cell disease. In an allogeneic transplant, used for conditions such as acute leukemia, patients receive cells from a stem cell donor.
Our comprehensive portfolio of novel therapies is designed to change the treatment landscape in both autologous and allogeneic transplant.
We’re developing medicines to improve all aspects of the transplant journey, including patient preparation, stem cell collection, cell dose and safe immune regeneration.